DKA

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1. Orders:

    1. imp: DKA

    2. ACT: CBR

    3. Vital signs: close observation

    4. Diet: NPO

    5. Condition: urgent

    6. IV line 2* fix

    7. CVS q1h

    8. ECG

    9. POM & CHM

    10. O2 therapy if SpO2<94%

    11. internal folly fix + check intake & output

    12. Check

        1. CBC, diff

        2. Na, K, Ca, P, Mg

        3. VBG, ABG

        4. U/A, U/C, BUN, Cr

        5. BS, HbA1c

        6. C-Peptide

        7. TSH, T3, T4

        8. ANTI-TTG IgA

        9. CRP, ESR,

        10. ALP

        11. B/C

    13. Check BS q1h

    14. check VBG q2h

    15. Check k q4h

    16. Check Na, K, Mg, Ca, P, BUN q4h

    17. IV hydration

        1. start with serum N/S 10-20 cc/kg IV infusion in 1 hours, repeat if diuresis was not started (distract it from the whole fluid that should be given)

        2. start 1000/10kh + 50/20 kg+ 20/kg cc IV maintenance

        3. add deficit: 10cc*w*10-7%

    18. Potassium

        1. k<3.2 : 80meq/lit kcl

        2. 3.2<k<4.5: 40meq/lit kcl

        3. 4.5<k<5.5: 20meq/lit kcl

        4. k>5.5: no KCl added

    19. Insulin

        1. only start when k>3.3

        2. Serum HS 500cc + 0.1 unit/kg regular insulin ?cc/hr IV infusion

        3. after resolving DKA, start insulin with 1unit/kg/day (1/3 basal, 2/3 regular) SQ with 30 minutes at least overlap with IV insulin

    20. HCO3

        1. if pH<6.9

        2. NaHCO3 (100mmol) in 400cc/2hr H2O + 20meq KCl IV infusion

    21. if + Headache, refractory vomiting, decreased LOC (in favor of brain edema)

        1. Mannitol 1gr/kg/15min, repeat 30 mins later if no response seen

2. Types of fluids:

    1. start hydration with N/S

    2. give insulin in HS

    3. BS<250 mg/dl ⇒ HS + DW5%

    4. 150<BS<200 ⇒ HS + DW7.5%

    5. 100<BS<150 ⇒ HS + DW10% + insulin 1/2

    6. BS<100 ⇒ HS + DW12.5% + insulin 1/2

3. DKA criteria

    1. BS>200

    2. VBG: pH<7.3, HCO3<15

    3. BHOP>3

    4. Ketonuria

4. Resolved DKA criteria

    1. pH>7.3

    2. HCO3> 15

5. Goal of BS:

    1. children: 150-180 mg/dl

    2. adult: 100-150 mg/dl

6.

April 16, 2026 (0)


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