Archive

Pain killers (analgesics)

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| Amp | Gel | Tab | Cap |

| — | — | — | — |

| Amp ketorolac | Piroxicam | methocarbamol 500 mg qid | Celexib bid or qd |

| Amp Robaxin | Diclofenac | Baclofen 10mg tds | Gabapentin 100, 300mg qd |

| Amp M.S 3-5 mg |  | Diclofenac 50, 100mg bid |  |

| Amp Dexamethasone |  | Naproxen 250, 500mg bid |  |

1. NSAIDs:

    1. celexib in almost all pt

    2. Naproxen in pt with CVDs

    3. add PPIs to NSAIDs

    4. If Peptic UD, do not prescribe NSAIDs

    5. alternative to NSAIDs are opioids like tramadol and codeine

2. Use Gabapentin for Radicular pains

3.

Drugs
April 23, 2026 (0)

Drug interactions

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1. Salbutamol/Seroflu ::: Propranolol ⇒ lower salbutamol effect

2. Antibiotics ::: OCP ⇒ lower OCP effects

3. Omeprazole :::: Clopidogrel ⇒ lower Plavix effect, use pantoprazole instead

4. Theophylline ::: Cipro/Oflox ⇒ theophylline poisoning

5. Gemfibrozil ::: atorvastatin ⇒ increase risk of myositis

6. Gentamycin ::: furosemide ⇒ ototoxicity

7. Sildenafil/Tadalafil ::: Nitrate ⇒ lowering BP

8. macrolides (erythro/ clarythro) ::: atorvastatin ⇒ increase level of atorvastatin

9. captopril/enalapril ::: spironolactone/triamterene ⇒ hyperkalemia

10. Warfarin ::: NSAIDs/cotri/metronidazole/phenytoin ⇒ warfarin toxicity

11. MTX ::: NSAIDs ⇒ increase MTX level

12. Methadone ::: SSRI/domperidone/clarythro ⇒ arrhythmias

13. ergotamine ::: sumatriptan ⇒ vasoconstriction

14. mebendazole ::: metronidazole ⇒ SJS

15. PROMETHAZINE ::: metoclopramide ⇒ extrapyramidal syndrome

16. Rakuten (isotretinoin) ::: tetracyclines/doxycycline/vitamin A

Drugs
April 16, 2026 (0)

Acetaminophen poisoning

1. Toxic dosage in:

    1. adults: 7.5 gr

    2. children: 150 mg/kg

2. check:

    1. AST, ALT, ALKP, PT, PTT, INR, BUN, Cr, VBG, Ca, P

    2. if AST/ALT >1000 ⇒ check them q6h

    3. if AST/ALT< 500 ⇒ check them daily

3. N-acetylcysteine 150 mg/kg in 1 hour then 50 mg/kg in 4 hours then 100 mg/kg in 16 hours IV

    or  N-acetylcysteine 140 mg/kg PO stat then 70 mg/kg PO q4h for 17 days

4. H.D if serum level AST/ALT >1000 or comatose or severe acidosis

5. Liver transplantation if pH< 7.3, PT>100 or Cr>3.3

DDx, Drugs
April 16, 2026 (0)

Pediatric supplements

1. for Formula

    1. Cow’s protein base:

        1. Bebelac

        2. NAN

    2. For hypersensitive child

        1. Aptamil pepti

    3. Based on age

        1. <6m/o ⇒ 1

        2. 6-12 m/o ⇒ 2

        3. >1y/o ⇒ 3

    4. suffix:

        1. Pepti ⇒ cow’s protein hypersensitivity

        2. HA ⇒ food reaction

        3. Pre ⇒ premature

        4. LF ⇒ lactase deficiency

        5. AR ⇒ reflux

Drugs, Pediatrics
April 16, 2026 (0)

Drugs in Pregnancy

1. GI drugs: B/C

    1. Safe:

        1. Bisacodyl

        2. Famotidine

        3. Metoclopramide

    2. Unsafe:

        1. Clinidium C

        2. Loperamide

        3. Diphenoxylate

        4. Dicyclomine

        5. Hyoscine

2. Respiratory drugs: B/C/D

    1. safe:

        1. diphenhydramine

    2. unsafe:

3. Antibiotics: B/C/D

    1. Safe:

        1. Cephalosporin

        2. Amoxicillin

        3. Ampicillin

        4. Erythromycin

        5. Azithromycin

        6. Penicillin

    2. Unsafe:

        1. Doxycycline

        2. Furazolidone

        3. Cotrimoxazole

        4. Tetracycline

4. Other drugs:

    1. safe:

        1. Acetaminophen

        2. Levothyroxine

        3. Ferrous sulfate

        4. Multivitamin mineral

        5. Folic acid

        6. Vit B1, A, B6, E, D, C

Drugs
April 16, 2026 (0)