Polycystic ovarian syndrome (PCOS)
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1. Symptoms
1. hirsutism, thick hair
2. irregular mensuration
3. acnes
4. obesity and metabolic syndrome
5. men pattern hair loss
6. oligomenorrhea
7. anovulation
2. Dx: sonography or hyperandrogenism symptoms
3. Imaging:
1. sonography of both ovaries, uterus and adnexa
4. Check
1. testestron, 17. hydroxy progestron, DHEA, Prolactin, LH, FSH
2. B-hCG
3. TSH, T3, T4
4. LDL, HDL, Total cholesterol, TG
5. CBC, FBS
6. ALT, AST, ALKP
5. Treatment
1. Tab OCP for 6 months
2. Metformin 500 mg bid for obesity, lipid profile and anovulation
3. Tab spironolactone 50mg bid for hirsutism
4. Ta clomiphene 50 mg qd from 5th days of cycle for 5 days, increase up to 100 mg, for ovulation
1. or tab letrozole start from 3rd day of mensuration for 5 days in cases resistant to clomiphene
5. Treat acnes
