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1. Look for underlying cause
2. Lab test:
1. CBC, diff
2. BUN, Cr
3. AST, ALT, ALKP, BILL (T, D)
4. TSH
3. Treatment
1. Cap doxepin 25mg qhs #10
1. or tab hydroxyzine 10 mg tds #20
2. or lotion calamine topical tds
3. or oint hydrocortisone 1%
2. if due to cholestasis
1. Sachet cholestyramine 4gr bid #30
2. Cap ursobil 300mg 2tab bid #60
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